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KMID : 0361020000430040426
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Korean Journal of Otolaryngology - Head and Neck Surgery
2000 Volume.43 No. 4 p.426 ~ p.429
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The Value of Routine Frozen Section Examination for Intraoperative Diagnosis of Thyroid Nodule
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Lee Hyung-Seok
Tae Kyung
Lee Eung-Jun
Lee Sang-Hoon
Jang Se-Jin
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Abstract
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Background : The value of routine frozen section examination for intraoperative diagnosis of thyroid
cancer and determination of the extent of thyroidectomy is controversial and needs to be evaluated on an
institution to institution basis.
Methods : Thyroidectomy with routine frozen section examination was carried out in 109 patients with
nodular thyroid disease, who also underwent FNAB. And these patients were retrospectively studied. A
direct comparison of the result of FNAB and frozen section examination with permanent pathologic finding
was done.
Result : The pathologic findings showed carcinoma in 32 patients, adenomatous hyperplasia in 57 patients,
adenoma in 19 patients and a Hrthle cell adenoma in one patient. The sensitivity, and accuracy were 86%,
100%, and 97%, respectively, for frozen section examination, and 76%, 100% and 93%, respectively, for
FNAB (p>0.05).
Conclusion : For patients who have undergone adequate FNAB, frozen section examination rarely affected
the intraoperative decision making in thyroid surgery and its routine use proved neither cost effective nor
time saving.
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KEYWORD
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Thyroid nodule, FNAB, Frozen section
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